Aflatoxins: Properties, Toxicity and Detoxification
نویسندگان
چکیده
منابع مشابه
Lead uptake, toxicity, and detoxification in plants.
Lead has gained considerable attention as a persistent toxic pollutant of concern,partly because it has been prominent in the debate concerning the growing anthropogenic pressure on the environment. The purpose of this review is to describe how plants take lead up and to link such uptake to the ecotoxicity of lead in plants.Moreover, we address the mechanisms by which plants or plant systems de...
متن کاملStructural Analysis and Biological Toxicity of Aflatoxins B1 and B2 Degradation Products Following Detoxification by Ocimum basilicum and Cassia fistula Aqueous Extracts
This study showed the comparison between Ocimum basilicum and Cassia fistula (leaves and branch) aqueous extracts for their ability to detoxify of aflatoxins B1 and B2 (AFB1; 100 μg L(-1) and AFB2; 50 μg L(-1)) by In Vitro assays and decontamination studies. Results indicated that O. basilicum leaves extract was found to be highly significant (P < 0.05) in degrading AFB1 and AFB2, i.e., 90.4 an...
متن کاملStructure-Activity Relationships in Toxicity and Carcinogenicity of Aflatoxins and Analogs1
Aflatoxins B! and G,, in single doses, were lethal and had similar relative potencies in the duckling (50% lethal dose, 0.73 mg/kg versus 1.18 mg/kg) and in the rat (50% lethal dose, 1.16 mg/kg versus 2 to 4 mg/kg). Aflatoxins B2 and G2 were less potent in the duckling (50% lethal dose, 1.76 mg/kg versus 2.83 mg/kg) and were nontoxic to rats at doses of 200 mg/kg. Aflatoxin BI induced hepatocel...
متن کاملStructure-activity relationships in toxicity and carcinogenicity of aflatoxins and analogs.
Aflatoxins B! and G,, in single doses, were lethal and had similar relative potencies in the duckling (50% lethal dose, 0.73 mg/kg versus 1.18 mg/kg) and in the rat (50% lethal dose, 1.16 mg/kg versus 2 to 4 mg/kg). Aflatoxins B2 and G2 were less potent in the duckling (50% lethal dose, 1.76 mg/kg versus 2.83 mg/kg) and were nontoxic to rats at doses of 200 mg/kg. Aflatoxin BI induced hepatocel...
متن کاملInfluence of Dietary Protein and Vitamin B12on the Toxicity and Carcinogenicity of Aflatoxins in Rat Liver1
The influence of dietary protein content and dietary vitamin B,, supplement on the hepatotoxicity and carcinogenicity of aflatoxin in rat liver was studied. In animals fed a low-protein diet, aflatoxin induced extensive toxic and carcinogenic effects. Cirrhosis was significantly pre vented to a certain level by vitamin B,_administration, but the incidence of cholangiofibrosis and hyperplastic n...
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ژورنال
عنوان ژورنال: Nutrition & Food Science International Journal
سال: 2018
ISSN: 2474-767X
DOI: 10.19080/nfsij.2018.06.555696